pentobarbital will reduce the extent or influence of loratadine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.pentobarbital decreases amounts of toremifene by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. CYP3A4 inducers increase level of toremifene metabolism, lowering the continual-s… Read More